Prof. Dr. M. Sendtner

Michael Sendtner
Institut für Klinische Neurobiologie
Universität Würzburg
Versbacherstr. 5, D-97078 Würzburg, Germany
Tel. ++49 (0931) 201-44000
Fax ++49 (0931) 201-44009






Research Interest:
Neurodegeneration: Signaling pathways for neuronal survival and axon growth; axonal mRNA transport, local protein synthesis in axons. 
Neurotrophic factors, pathomechanisms of neurodegeneration, role of neurotrophic factors in neural development and synaptic plasticity.

Bibliometrics Web of Science (April 2018): ISI-indexed 327, Sum Cited (without self citations) 19,824, Average Citations per article 63,75, h-index 73

Education, Qualifications and Professional History
Since 2000    Full Professor (C4); Chairman Institute of Clinical Neurobiology, University of Würzburg, Chairman DFG funded SFB/Collaborative Research Center  581 “Molecular models for diseases of the nervous system” from 2000-2012.
1995-1999    Professor (C3) of Neurobiology at the University of Würzburg, Head of the “Klinische Forschergruppe (DFG) für Neuroregeneration”
1992        Habilitation (Dr. med. habil., Experimental Neurology), TU Munich
1987-1994    Research Associate, MPI for Psychiatry, Munich (with H. Thoenen)
1985-1987    Fellow, Max-Planck-Society, Dept. of Neurochemistry, Max-Planck-Institute
1984-1985    Resident, Dept. Neurology, TU Munich (with A. Struppler)
1984        MD; Dept of Internal Medicine, Cardiology, TU Munich
1978-1984    Universities of Regensburg and TU Munich, Graduation from Medical School

Service as Consultant and Advisor

Member Senate Deutsche Forschungsgemeinschaft (DFG), 2011-2017
Member DFG Senate Commission on Key Questions in Clinical Research 2013-2015
Member Panel Neuroscience German Science Foundation (DFG) 2005-11
Scientific Advisory Board, Hermann und Lilly Schilling Foundation, Germany, since 2015.


Member Programme and Publication Committees, Society for Neuroscience, SfN, 2010-2016
Member ERC Review Panel Consolidator Grants, LS5 Neuroscience, 2015, 2017
Member Peer Review College, Wellcome Trust, UK, 2013-2017
Scientific Advisory Board, British MND Association, 2002-2006
Member Review Panel Brain Canada 2015
Member TCP Panel 2017
Member Panel Italian Research Foundation for ALS Research, ARISLA, 2017

1985 Long-term Fellowship, Max-Planck Society, Germany
1993 Myopathy-Award (German Society for Muscular Diseases),
1994 Wilhelm-Vaillant Award, Ludwig Maximilians University of Munich, Germany
2007 Sobek Award for Multiple Sclerosis Research, Sobek Foundation

Most cited publications (more than 400 citations)

  1. Sendtner, M., G.W. Kreutzberg, and H. Thoenen: Ciliary neurotrophic factor (CNTF) prevents the degeneration of motorneurons after axotomy. Nature 345, 440-441, 1990.
  2. Sendtner, M., B. Holtmann, R. Kolbeck, H. Thoenen, and Y.-A. Barde: Brain-derived neurotrophic factor prevents the death of motoneurons in newborn rats after nerve-section. Nature 360, 757-759, 1992.
  3. Lüttiken,C., U.M. Wegenka, J. Yuan, J. Buschmann, C. Schindler, A. Ziemiecki, A.G. Harpur, A.F. Wilks, K. Yasukawa, T. Taga, T. Kishimoto, G. Barbieri, S. Pellegrini, M. Sendtner, P.C. Heinrich and F. Horn. Association of transcription factor APRF and protein kinase jak1 with interleukin-6 signal transducer gp 130.Science 263, 89-92, 1994.
  4. Stöckli, K.A., F. Lottspeich, M. Sendtner, P. Masiakowski, P. Carroll, R. Götz, D. Lindholm, and H. Thoenen: Molecular cloning, expression and regional distribution of rat ciliary neurotrophic factor. Nature 342, 920-923, 1989.
  5. Arakawa, Y., M. Sendtner, and H. Thoenen: Survival effect of ciliary neurotrophic factor (CNTF) on chick embryonic motoneurons in culture: Comparison with other neurotrophic factors and cytokines, J. Neurosci. 10(11), 3507-3515, 1990.
  6. Sendtner, M., H. Schmalbruch, K.A. Stöckli, P. Carroll, G.W. Kreutzberg, and H. Thoenen: Ciliary neurotrophic factor prevents degeneration of motor neurons in mouse mutant progressive motor neuronopathy. Nature 358, 502-504, 1992.
  7. Masu, Y., E. Wolf, B. Holtmann, M. Sendtner, G. Brem, and H. Thoenen. Disruption of the CNTF gene results in motoneuron degeneration. Nature 365, 27-32, 1993.